Peer-reviewed medical journal articles on cluster headache and related conditions.

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Article topics

  • Resolution of Cluster Headaches in a Female Using Koren Specific Technique February 9, 2011
    This case study reports on a female patient suffering from cluster headaches who was successfully treated with the Koren Specific Technique.
  • Cluster Headache—Acute and Prophylactic Therapy February 1, 2011
    Cluster headache (CH) pain is the most severe of the primary headache syndromes. It is characterized by periodic attacks of strictly unilateral pain associated with ipsilateral cranial autonomic symptoms. The majority of patients have episodic CH, with cluster periods that typically occur in a circannual rhythm, while 10% suffer from the chronic form, with no ...
  • Cardiac safety in cluster headache patients using the very high dose of verapamil (≥720 mg/day) January 22, 2011
    Use of high doses of verapamil in preventive treatment of cluster headache (CH) is limited by cardiac toxicity. We systematically assess the cardiac safety of the very high dose of verapamil (verapamil VHD) in CH patients.
  • Trigeminal TRPs and the Scent of Pain January 1, 2011
    The neurological mechanisms leading to headache pain are complex and poorly understood. Genetic studies of familial migraine conditions have provided important insights into the potential physiological causes underlying headache conditions.
  • Inhaled Oxygen and Cluster Headache Sufferers in the United States: Use, Efficacy and Economics: Results From the United States Cluster Headache Survey November 10, 2010
    Several small clinic and community-based investigations have indicated that more than 50% of CH patients have never used oxygen for the treatment of their headaches. This statistic is alarming and the reasons why they have not tried oxygen have not been determined.
  • Cognitive-Behavioral Therapy and Neuroscience: Towards Closer Integration October 1, 2010
    The aim of this review article is to provide an integrative perspective by combining basic assumptions of cognitive behavioral therapy (CBT) with neuroscience research results. In recent years, interdisciplinary research in the field of neuroscience has expanded our knowledge about neurobiological correlates of mental processes and changes occurring in the brain due to therapeutic interventions. ...
  • Cluster Headache – Diagnosis and Treatment April 1, 2010
    Cluster headache is a rare yet exquisitely painful primary headache disorder occurring in either episodic or chronic patterns. The unique feature of cluster headache is the distinctive circadian and circannual periodicity in the episodic forms
  • The non-hallucinogen 2-bromo-lysergic acid diethylamide as preventative treatment for cluster headache: An open, non-randomized case series March 26, 2010
    Cluster headache (CH) is a stereotyped primary headache characterized by strictly unilateral severe orbital or periorbital pain and categorized as either episodic or chronic (1,2). Its prevalence is 0.1% (3). Oxygen and sumatriptan are the treatments of choice for individual attacks, whereas verapamil, lithium, corticosteroids and other neuromodulators can suppress attacks during cluster periods (1)
  • Safety and Efficacy of Repeated-Dose Intravenous Ketamine for Treatment-Resistant Depression January 15, 2010
    A single sub-anesthetic (intravenous) IV dose of ketamine might have rapid but transient antidepressant effects in patients with treatment-resistant depression (TRD). Here we tested the tolerability, safety, and efficacy of repeated-dose open-label IV ketamine (six infusions over 12 days) in 10 medication-free symptomatic patients with TRD who had previously shown a meaningful antidepressant response to ...
  • High-Flow Oxygen for Treatment of Cluster Headache December 9, 2009
    A double-blind, randomized, placebo-controlled crossover trial of 109 adults (aged 18-70 years) with cluster headache as defined by the International Headache Society. Patients treated 4 headache episodes with high-flow inhaled oxygen or placebo, alternately. Patients were randomized to the order in which they received the active treatment or placebo. Patients were recruited and followed up ...