Cluster headache is characterized by unilateral attacks of severe pain accompanied by cranial autonomic features.
Apart from these there are also sleep-related complaints and strong chronobiological features. The interaction
between sleep and headache is complex at any level and evidence suggests that it may be of critical importance in
our understanding of primary headache disorders. In cluster headache several interactions between sleep and the
severe pain attacks have already been proposed. Supported by endocrinological and radiological findings as well as
the chronobiological features, predominant theories revolve around central pathology of the hypothalamus. We
aimed to investigate the clinical presentation of chronobiological features, the presence of concurrent sleep
disorders and the relationship with particular sleep phases or phenomena, the possible role of hypocretin as well as
the possible involvement of cardiac autonomic controlRead More →

Optimal management of patients with classical trigeminal neuralgia (TN) requires specific treatment programs and close collaboration between medical, radiological and surgical specialties. Organization of such treatment programs has never been described before. With this paper we aim to describe the implementation and feasibility of an accelerated cross-speciality management program, to describe the collaboration between the involved specialties and to report the patient flow during the first 2 years after implementation. Finally, we aim to stimulate discussions about optimal management of TN.Read More →

Data on clinical differences between episodic (eCH) and chronic cluster headache (cCH) and accompanying migraine features are limited. History and clinical features of 209 consecutive cluster headache patients (144 eCH, 65 cCH; male:female ratio 3.4 : 1) were obtained in a tertiary headache centre by face-to-face interviews. Relationship between occurrence of accompanying symptoms, pain intensity, comorbid migraine, and circannual and circadian rhythmicity was analyzed.Read More →

A 34-year-old man with right-sided cluster headache presented with a stroke from right-sided moyamoya. Following surgery on the right, both moyamoya and cluster headache remitted, but eighteen months later a cluster attack and symptoms of cerebral ischemia from moyamoya recurred on the left. Again, following surgery on the left, both moyamoya symptoms and cluster attacks disappeared. Cluster headache secondary to moyamoya has not previously been described.
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Head pain arises within the trigeminal nociceptive system. Current theories propose that the trigeminal system is intimately involved in the pathogenesis of migraine. Short-latency responses can be recorded in sternocleidomastoid muscles after stimulation of the trigeminal nerve (trigemino-cervical reflex). This brainstem reflex could be a suitable method to evaluate the trigeminal system in migraine and CH.Read More →