Anti-inflammatory Protocol

Disclaimer: The following Anti-Inflammatory Regimen, treatment protocol and dosing guide to prevent cluster headaches are provided for information purposes only. Discuss them with your primary care physician (PCP) or neurologist whoever is most aware of your overall medical health and other prescribed medications before starting this regimen.

If possible, have your PCP or neurologist schedule a lab test for 25-Hydroxyvitamin D, a.k.a. 25(OH)D before starting this regimen. If not, don’t delay, start this regimen, then get the lab test. This lab test measures the serum concentration of 25-Hydroxyvitamin D, also called 25(OH)D, (calcidiol). This is a metabolite of vitamin D3.  The normal reference range for 25(OH)D in the US is 30-100 ng/mL, (50-200 nmol/L in the EU, UK and elsewhere.) However, cluster headache patients presenting with active cluster headache have tested as high as 53 to 61 ng/mL, (132.5 to 152.5 nmol/L).
Moreover, cluster headache patients who have used this regimen and experienced a significant reduction in the frequency and severity of their cluster headache attacks or gone pain free have all tested in a range of 60 to 110 ng/mL (150 to 275 nmol/L). If you think your PCP or neurologist will have questions about this regimen, please feel free to take a copy of this post with you to the next appointment.


Omega 3 Fish Oil (EPA 360 mg/day, DHA 240 mg/day) 2000 to 2400 mg/day
Vitamin D3* 10,000 IU/day
Calcium** (calcium citrate preferred) 500 mg/day
Magnesium (magnesium citrate or magnesium gluconate) 400 mg/day
Vitamin K2*** 120 mcg/day
Vitamin A**** 900 mcg (3,000 IU) for men
700 mcg (2,333 IU) for women
Zinc 10 mg/day
Boron 1 mg/day


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